吴萌,博士,副研究员
Email: moew@sdu.edu.cn
【教育经历】
2014.09-2019.01清华大学,生物学,博士
2010.09-2014.07北京理工大学,应用化学,大学本科
【工作经历】
2020.06-2022.09清华大学,生命科学学院,博士后
2022.10-至今 山东大学,基础医学院,副研究员
【研究方向】
长期从事冷冻电镜结构生物学研究,主要研究生命过程中关键生物大分子机器的结构与功能,尤其是在线粒体领域。
【奖项荣誉】
2018年 北京市科学技术奖 二等奖
2016年2016年度中国生命科学领域十大进展
【代表性论文】
1.Meng Wu*, Jinke Gu*, Runyu Guo*, Yushen Huang*, and Maojun Yang (2016). Structure of Mammalian Respiratory Supercomplex I1III2IV1.Cell167, 1598-1609.
2.Meng Wu*, Jinke Gu, Shuai Zong, Runyu Guo, Tianya Liu, and Maojun Yang (2020). Research journey of respirasome.Protein & Cell11(5):318-338
3.Jinke Gu*,Meng Wu*, Runyu Guo*, Kaige Yan, Jianlin Lei, Ning Gao, and Maojun Yang (2016). The architecture of the mammalian respirasome.Nature537, 639–643.
4.Runyu Guo*, Shuai Zong*,Meng Wu*, Jinke Gu*, and Maojun Yang (2017). Architecture of Human Mitochondrial Respiratory Megacomplex I2III2IV2.Cell170, 1247-1257.
5.Shuai Zong*,Meng Wu*, Jinke Gu*, Tianya Liu*, Runyu Guo*, and Maojun Yang (2018). Structure of the intact 14-subunit human cytochrome c oxidase.Cell Research28, 1026–1034.
6.Shuai Zong*, Jinke Gu*, Tianya Liu*, Runyu Guo*,Meng Wu*, and Maojun Yang (2018). UQCRFS1N assembles mitochondrial respiratory complex-III into an asymmetric 21-subunit dimer.Protein & Cell9, 586-591
7.Xinyue Zhang*,Meng Wu*, Wei Zhuo*, Jinke Gu, Sensen Zhang, Jingpeng Ge, and Maojun Yang (2015). Crystal structures of Bbp from Staphylococcus aureus reveal the ligand binding mechanism with Fibrinogen α.Protein & Cell6, 757-766.
8.Runyu Guo*, Jinke Gu,Meng Wu, and Maojun Yang (2016). Amazing structure of respirasome: unveiling the secrets of cell respiration.Protein & Cell7, 854-865.
9.Runyu Guo*, Jinke Gu, Shuai Zong,MengWu, and Maojun Yang (2018). Structure and mechanism of mitochondrial electron transport chain.Biomedical Journal41, 9-20.
10.Xiaolin Wang*,Meng Wu, Jie Ding, Zesheng Li, and Kening Sun (2014). Periodic density functional theory study on the interaction mode and mechanism of typical additives with TiO2 substrates for dye-sensitized solar cell applications.Journal of Power Sources246, 10-18.